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KMID : 0931320140140010013
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대한상부위장관.헬리코박터학회지
2014 Volume.14 No. 1 p.13 ~ p.17
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Pharmacological Therapy of Peptic Ulcer
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Oh Jung-Hwan
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Abstract
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Peptic ulcer disease is one of the most commonly encountered diseases. Despite the decrease of Helicobacter pylori infection, the use of aspirin and non-steroidal anti-inflammatory drugs has increased in recent years. Peptic ulcer bleeding is a common emergency associated with high mortality. As an adjunct to endoscopic treatment, acid suppression with proton pump inhibitors (PPIs) is im-portant in the management of peptic ulcer bleeding. A high dose intravenous PPI is effective in reducing rebleeding and the need for surgery. However, data about non-high dose intravenous PPIs are limited. In addition, novel PPIs are focused in this review, since progress has been made regarding new PPIs.
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KEYWORD
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Peptic ulcer, Peptic ulcer hemorrhage, Proton pump inhibitors, Therapy
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